What Are The Potential Side Effects Of Kratom?

Like any other organic chemical, kratom may not be suitable for everyone or in every condition. When you take in a substance for the first time your body gives you a trigger warning before matters get worse. You just don’t have to ignore that. Many consumers swear to the benefits of kratom but always advise to start with less and continue only if your body adapts to it. Side effects with kratom can be mild from dry mouth or runny nose to as severe as liver, or brain damage.

However, there are fewer chances of experiencing these effects when you stick to the recommended dosage and avoid co-administration of other drugs. are there any side effects of kratom

In this post, we will address the kratom side effects that are most commonly associated with the intake of these evergreen tree leaves.

Kratom cause cardiovascular discomforts

Is it true that kratom causes heart palpitations, heart attack, abnormal heart rhythms, or high blood pressure? While many users advocate its relieving and relaxing properties, major concerns indicate that its overdoses are indicated in various cardiovascular disorders. It has been found that its increasing amount and prolonged use can interfere with QTc interval in a dose-dependent manner, and these effects can be aggravated if the herb is consumed along with alcohol. 

Many other researchers claim that the most pronounced cardiotoxic effects of this plant are tachycardia and hypertension. Associated risk factors such as smoking and addiction to opioids can worsen the situation. They can also lead to many other problems such as left ventricular hypertrophy, cardiac arrhythmia, cardiomegaly, and cardiomyopathy. The overall discussion on the damaging effects of Mitragyna speciosa on the cardiovascular system concludes that it is more associated with overdose and co-administration of other risk factors than with kratom alone.

Kratom can cause you to lose weight

Some consumers believe that kratom can cause weight loss, and they say this by affirmation based on anecdotal research. Nevertheless, there is no official research that supports this claim. True or not, this effect of kratom can both be treated as a side effect or a primary effect making kratom consumption a healthy way of losing weight.

Consumers contribute this property of this magical herb to the two most important alkaloids, 7-hydroxymitragynine, and Mitragynine. According to them, the high intake of both these chemical compounds reduces the appetite and thus minimizes your calorie intake. This property may differ with different strains. Some strains can actually increase your appetite. So, the selection of the right strain is crucial here. If you do not want to lose weight, you may want to discontinue using a strain that reduces your appetite.

Kratom might lead to dependency

Kratom is currently under FDAs critical eye because of its tendency to become a substance of abuse or develop dependency in its consumers. Since it interacts with opioid brain receptors, it can mimic its effects. It can cause dependence and withdrawal symptoms if discontinued after prolonged use. According to the National Institute of Drug Abuse, many users have reported becoming addicted to kratom. The most common withdrawal symptoms that are observed are muscle aches, aggression, irritability, runny nose, and insomnia.

Kratom can be toxic for the liver

Our liver plays a role in the regulation and excretion of various chemicals. When any chemical is consumed more than your liver can regulate, it leads to conditions like toxicity and cirrhosis. The prolonged use of kratom tea has been indicated in various liver disorders. Even the healthiest of the supplements can behave as toxins when taken in excess. Liver dysfunctions due to Mitragyna speciosa come out as abnormal liver tests, lethargy or pruritus, dark colored urine, followed by Jaundice. Nevertheless, the injury has been found to go away once the supplement is discontinued. Additionally, the incidence is more common among people who use other drugs of abuse with the herb.

Kratom is thought to lower testosterone levels

According to research conducted by the National Institute of Drug Abuse, kratom was casually associated with an increase in serum Prolactin and a decrease in testosterone level. However, there still lacks enough evidence to support a clear relationship between kratom and lower testosterone levels. Research made in July 2018 published in the Journal of Ethnopharmacology says that regular kratom tea/juice consumption over prolonged periods (>2 years) was not associated with testosterone impairing effects in humans.

Various other research results failed to establish a direct link between kratom and the decreasing levels of gonadotropins even with regular daily intake. Many consumers say that healthy male adults do not experience any effect on their circulating testosterone, FSH, or LH levels. Any abnormality with testosterone level is related to the co-administration of other addictive drugs.

Kratom causes erectile dysfunction

There are no scientific statements that establish a direct association between kratom intake and Erectile dysfunction. Sexual arousal, however, is a complicated process involving factors such as emotions, nerves, hormones, brain, muscles, and blood vessels. Thus, a change in any of these can overall affect sexual performance. Though kratom may not directly influence the process of erection in men, it influences the associated factors such as libido and hormones. The two most important hormones in maintaining sexual drive and hence erection are dopamine and serotonin. According to a study conducted by the National Institutes of Health, people who took the drug experienced spikes in dopamine and serotonin levels

Dopamine is a powerful neurotransmitter that interferes with emotions and motor control. On the other hand, serotonin has a direct effect on ejaculation. It sends persistent signals throughout the brain to help maintain an erection. Thus, the only role this herb has in causing erectile dysfunction is meddling with the roles of the nervous system. It is important to note that not all men using the herb experience changes in libido or hormone levels.

Kratom causes hair loss

Concerns of people regarding kratom leading to hair loss are increasing. There are so many speculations over the social media platforms, whether it is true or not or what in kratom causes hair loss. Though there is no substantial evidence that the herb is involved in causing hair loss, various consumers have reported it and say this with conviction since they found their hair growing back to normal on leaving the herb.

 Those who strongly believe in this connection suggest a number of reasons, such as the immunostimulant effects of the herb, the non-conventional ways ( other than chewing leaves and brewing into tea), and the recently reported presence of heavy metals in kratom products.

Kratom and headaches

Again, no scientific evidence directly establishes a linkage between kratom and headache. All the research that is available comes from individuals that experienced headaches while they were using other drugs along with Mitragyna speciosa. In many cases, kratom headaches are due to the user’s carelessness, such as not drinking enough water to process kratom, getting bad sleep, using a poor quality strain, overdosing, and co-administering narcotics. In other cases, what you call a headache may be a kratom hangover that you may experience a day after the intake. These hangovers are quite common with overdosing.


Kratom overdosing or co-administration with other drugs thus can lead to headaches, general weakness, nausea, vomiting, or diarrhea. It can also cause lethargy, irritability, anxiety, sweating, loss of appetite, dry mouth, itching, aches, pains, or muscle cramps. In order to avoid these side effects, be sure to sleep well, drink enough water, and consume only quality kratom strains. Also, refrain from overstepping your recommended dosage.